OCLN Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70321
宿主: Rabbit
反应性: M
应用: WB
Overview
| Synonyms | BLCPMG,FLJ08163,FLJ18079,FLJ77961,FLJ94056,MGC34277,Occludin,Ocln,OCLN,Phosphatase 1 regulatory subunit 115,PPP1R115,PTORCH1,Tight junction protein occludin,OCLN抗体 |
| Swissprot | Q61146,Q6P6T5 |
| Source | Rabbit |
| Reactivity | Mouse |
| Immunogen | Recombinant protein corresponding to Mouse occludin |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.56 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. Cell junction>tight junction. |
| Tissue specificity | Localized at tight junctions of both epithelial and endothelial cells. Highly expressed in the testis, kidney, lung, liver and brain. Not detected in skeletal muscle, spleen and heart.Highest expression level in brain blood vessel. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | Occludin is an integral membrane protein located at the tight junction. It is a tetraspanin protein with four transmembrane domains,intracellular N and C termini and two extracellular loops. Occludin plays a role in the formation and regulation of the tight junction paracellular permeability barrier. Occludin can exist in different isoforms,owing to modifications at the posttranscriptional and posttranslational levels . |
客户发表文献
- 文献: Kolaviron protects against nigrostriatal degeneration and gut oxidative damage in a stereotaxic rotenone model of Parkinson’s disease
样品类型: Tissue homogenate - 文献: Nigral and ventral tegmental area lesioning induces testicular and sperm morphological abnormalities in a rotenone model of Parkinson’s disease
样品类型: Tissue
