OLR1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10934
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | C-type lectin domain family 8 member A,CLEC8A,hLOX 1,hLOX-1,Lectin like oxidized LDL receptor 1,Lectin like oxLDL receptor 1,Lectin type oxidized LDL receptor 1,Lectin-like oxidized LDL receptor 1,Lectin-like oxLDL receptor 1,Lectin-type oxidized LDL receptor 1,low density lipoprotein oxidized,receptor 1,LOX-1,LOXIN,Olr1,OLR1,Ox LDL receptor 1,Ox-LDL receptor 1,Oxidised low density lipoprotein (lectin like) receptor 1,Oxidized low density lipoprotein receptor 1,Oxidized low density lipoprotein receptor 1 soluble form,Oxidized low-density lipoprotein receptor 1,SCARE1,Scavenger receptor class E,member 1,SLOX1,soluble form,SR-EI,OLR1抗体 |
| Swissprot | P78380 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human OLR1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Secreted. A secreted form also exists. |
| Tissue specificity | Expressed at high level in endothelial cells and vascular-rich organs such as placenta, lung, liver and brain, aortic intima, bone marrow, spinal cord and substantia nigra. Also expressed at the surface of dendritic cells. Widely expressed at intermediate and low level. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants. |
