P2RX3 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70216
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
| Synonyms | ATP receptor,MGC129956,P2rx3,P2RX3,P2X purinoceptor 3,P2X receptor subunit 3,P2X3,Purinergic receptor,Purinergic receptor P2X ligand gated ion channel 3,Purinergic receptor P2X3,Purinoceptor P2X3,P2RX3抗体 |
| Swissprot | Q3UR32,P49654 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse P2X3 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:500-1:2000; |
| Concentration | 420 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane, Membrane |
| Tissue specificity | Highest expression level in dorsal root ganglion |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. |
