PAI1 Polyclonal Antibody
| 规格： | / 50μL / 100μL |
| 价格： | / ￥1010 / ￥1640 |
货号：E-AB-40651
货期：咨询
宿主: Rabbit
反应性: R
应用: WB
Overview
| Synonyms | Plasminogen activator inhibitor 1, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1, SERPINE1, PLANH1 |
| Swissprot | P20961 |
| Source | Rabbit |
| Reactivity | Rat |
| Immunogen | Recombinant Rat PAI1 protein expressed by Mammalian |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:250-1:500; |
| Concentration | 4.3mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading.Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis. |
