PAX2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19302
宿主: Rabbit
反应性: H,M
应用: WB
Overview
Synonyms | FSGS7,Paired box 2,Paired box gene 2,paired box homeotic gene 2,paired box protein 2,Paired box protein Pax 2,Paired box protein Pax-2,Paired box protein Pax2,PAPRS,Pax 2,PAX2抗体 |
Swissprot | Q02962 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human PAX2 |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:500-1:2000; |
Concentration | 0.48mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nuclear |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. |