PAX5 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19303
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | B cell lineage specific activator,B cell lineage specific activator protein,B cell specific activator protein,B cell specific transcription factor,B-cell-specific transcription factor,BSAP,EBB-1,KLP,Paired box 5,Paired box gene 5 (B cell lineage specific activator protein),Paired box gene 5 (B cell lineage specific activator),Paired box gene 5,Paired box homeotic gene 5,Paired box protein Pax 5,Paired box protein Pax-5,Paired domain gene 5,PAX 5,PAX5,PAX5,Transcription factor PAX 5,PAX5抗体 |
| Swissprot | Q02548 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human PAX5 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 0.84mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | PAX5,also named B-cell specific activator protein (BSAP),is a member of the highly conserved paired box (PAX)-domain family of transcription factors. PAX5 is essential in normal B-cell lymphopoiesis. It is expressed in pro-B,pre-B and mature B lymphocytes but not in plasma cells. PAX5 is a common target in leukemogenesis of B-ALL ( B-lineage acute lymphoblastic leukemia) along with CDKN2A. Owing to its frequent deletion in B-ALL,PAX5 could be used as one of the molecular markers in diagnosis and monitoring of the disease. This antibody is specific to PAX5. It will not cross react with other PAX members. |
