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PAX6 Polyclonal Antibody

规格: / 60μL / 120μL / 200μL
价格: / ¥1380 / ¥2220 / ¥3580

货号:E-AB-61653

宿主: Rabbit

反应性: H,M,R

应用: IF

  • 详情
  • 文献(1)
  • Overview

    Synonyms AN,AN2,ASGD5,D11S812E,FVH1,MGDA,WAGR,PAX6,PAX6抗体
    Swissprot P26367
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Recombinant fusion protein of human PAX6 (NP_000271.1).
    Application IF
    Recommended dilution IF,,1:50-1:200
    Concentration 1 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20°C. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3
    Background This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.
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