PAX6 Polyclonal Antibody
规格: | / 60μL / 120μL / 200μL |
价格: | / ¥1380 / ¥2220 / ¥3580 |
货号:E-AB-61653
宿主: Rabbit
反应性: H,M,R
应用: IF
Overview
Synonyms | AN,AN2,ASGD5,D11S812E,FVH1,MGDA,WAGR,PAX6,PAX6抗体 |
Swissprot | P26367 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant fusion protein of human PAX6 (NP_000271.1). |
Application | IF |
Recommended dilution | IF,,1:50-1:200 |
Concentration | 1 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20°C. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Background | This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms. |