PDE5A Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16696
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | 5''-cyclic phosphodiesterase,CGB PDE,CGB-PDE,CGBPDE,cGMP binding cGMP specific 3' 5' cyclic nucleotide phosphodiesterase,cGMP binding cGMP specific 35 cyclic nucleotide phosphodiesterase,cGMP binding cGMP specific phosphodiesterase,cGMP binding/cGMP specific phosphodiesterase,cGMP specific 3'5' cyclic phosphodiesterase,cGMP specific phosphodiesterase PDE5A2,cGMP specific phosphodiesterase type 5A,cGMP-binding cGMP-specific phosphodiesterase,cGMP-specific 3'',CN5A,CN5N,PDE 5,PDE 5A,PDE5,Pde5a,PDE5A,PDE5A1,Phosphodiesterase 5A,Phosphodiesterase 5A cGMP specific,Phosphodiesterase isozyme 5,PDE5A抗体 |
| Swissprot | O76074 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human PDE5A |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 0.5mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol |
| Tissue specificity | Expressed in aortic smooth muscle cells, heart, placenta, skeletal muscle and pancreas and, to a much lesser extent, in brain, liver and lung. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. |
