PDHA1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52930
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | ODPA,PDH,PDHA,PDHA1,PDHCE1A,PDHE1 A type I,PDHE1-A type I,PHE1A,Pyruvate Dehydrogenase (lipoamide) alpha 1,Pyruvate dehydrogenase complex,E1 alpha polypeptide 1,Pyruvate Dehydrogenase E1 alpha,Pyruvate dehydrogenase E1 component subunit alpha,somatic form,mitochondrial,PDHA1抗体 |
| Swissprot | P08559 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human PDHA1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:300; |
| Concentration | 0.9mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion matrix. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | PDHA1(Pyruvate dehydrogenase E1 component subunit alpha,somatic form,mitochondrial) is also named as PHE1A.It is one of the 3 enzymes of the pyruvate dehydrogenase complex which is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA.It has 4 isoforms produced by alternative splicing.Defects in PDHA1 are a cause of pyruvate dehydrogenase E1-alpha deficiency (PDHAD) and X-linked Leigh syndrome (X-LS). |
