Phospho-CREB1 (Ser133) Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL |
价格: | / ¥630 / ¥1510 / ¥2415 |
货号:E-AB-20849
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC-p,IF
Overview
Synonyms | Active transcription factor CREB,cAMP response element binding protein 1,cAMP response element binding protein,cAMP responsive element binding protein 1,cAMP-responsive element-binding protein 1,CREB,CREB-1,CREB1,CREB1,Cyclic AMP-responsive element-binding protein 1,MGC9284,OTTHUMP00000163864,OTTHUMP00000163865,OTTHUMP00000206660,OTTHUMP00000206662,OTTHUMP00000206667,Transactivator protein,CREB-1 (phospho Ser133)磷酸化抗体 |
Swissprot | P16220 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthesized peptide derived from human CREB-1 around the phosphorylation site of Ser133 |
Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),IF |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300;IF,,1:100-1:300; |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
Background | This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity. |
Images
Western Blot analysis of various cells using Phospho-CREB1 (Ser133) Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human uterus tissue using Phospho-CREB1 (Ser133) Polyclonal Antibody at dilution of 1:200
Immunofluorescence analysis of Mouse lung tissue using Phospho-CREB1 (Ser133) Polyclonal Antibody at dilution of 1:200