Phospho-ERK 1/2 (Thr202/Tyr204) Polyclonal Antibody
规格: | / 60μL / 120μL / 200μL |
价格: | / ¥1380 / ¥2220 / ¥3300 |
货号:E-AB-70310
宿主: Rabbit
反应性: M,R
应用: WB
Overview
Synonyms | MAPK3,ERK1,PRKM3,Mitogen-activated protein kinase 3,MAP kinase 3,MAPK 3,ERT2,Extracellular signal-regulated kinase 1,ERK-1,Insulin-stimulated MAP2 kinase,MAP kinase isoform p44,p44-MAPK,Microtubule-associated protein 2 kinase,ERK1/2磷酸化抗体 |
Swissprot | P63085,Q63844 |
Source | Rabbit |
Reactivity | Mouse,Rat |
Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse ERK2 |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:500-1:2000; |
Concentration | 1.1 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm, Cytoskeleton, Membrane, Nucleus |
Tissue specificity | Widely expressed.Highest expression level in olfactory tubercle |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Background | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. |
客户发表文献
- 文献: Sesamol-Loaded PLGA Nanosuspension for Accelerating Wound Healing in Diabetic Foot Ulcer in Rats
样品类型: Wound tissue - 文献: Dehydrozingerone promotes healing of diabetic foot ulcers: a molecular insight
样品类型: foot ulcer - 文献: α2,6-Sialylation mediates hepatocellular carcinoma growth in vitro and in vivo by targeting the Wnt/β-catenin pathway
样品类型: Cell lysate - 文献: Curcumin Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Neutrophil Extracellular Traps Formation
样品类型: hepatic - 文献: Fermented Unpolished Black Rice (Oryza sativa L.) Inhibits Melanogenesis via ERK, p38, and AKT Phosphorylation in B16F10 Melanoma Cells
样品类型: Cell sample