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PKM2 Polyclonal Antibody

规格: / 50μL / 100μL
价格: / ¥1010 / ¥1640

货号:D-AB-10309L

货期:咨询

宿主: Rabbit

反应性: H

应用: WB

  • 详情
  • Overview

    Synonyms Pyruvate kinase PKM,Cytosolic thyroid hormone-binding protein,Opa-interacting protein 3,Pyruvate kinase 2/3,Pyruvate kinase muscle isozyme,Threonine-protein kinase PKM2,Thyroid hormone-binding protein 1 (THBP1),PKM,OIP3,PK2,PK3,PKM2
    Swissprot P14618
    Source Rabbit
    Reactivity Human
    Immunogen Recombinant Human PKM2 Protein expressed by E.coli
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:500-1:1000;
    Concentration 1mg/mL
    Clonality Polyclonal

    Properties

    Isotype IgG
    Purification Antigen Affinity Purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
    Background This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP,generating ATP and Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein,a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells,suggesting a role of this protein in bacterial pathogenesis.
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