PODXL Polyclonal Antibody
| 规格： | / 50μL / 100μL |
| 价格： | / ￥1010 / ￥1640 |
货号：D-AB-10420L
货期：咨询
宿主: Rabbit
反应性: H
应用: WB
Overview
| Synonyms | GCTM 2 antigen,Gp200,PC,PCLP,PCLP 1,PCLP1,Podocalyxin,podocalyxin like,Podocalyxin like protein 1,PODXL,RCC marker,Renal Cell Carcinoma marker,TRA 1 81,TRA 1 60,TRA-1-60 |
| Swissprot | O00592 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant Human PODXL protein expressed by E.coli |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:250-1:500; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | Podocalyxin,also known as podocalyxin-like protein 1 (PODXL or PCLP1),is a transmembrane glycoprotein belonging to the CD34 family of sialomucins. Podocalyxin was originally identified as the major sialoprotein on podocytes of the kidney glomerulus,but was later found to be expressed on vascular endothelial cells and early hematopoietic progenitors. It Involved in the regulation of both adhesion and cell morphology. In addition,podocalyxin is highly expressed in embryonic stem cells and aberrant expression of podocalyxin has been implicated in a wide range of cancers. Podocalyxin is a protein with a peptide bone of ∼55.5 kDa that undergoes a post‐translational glycosylation,the different molecular mass of podocalyxin indicates the extent and variability of glycosylation patterns |
