PPARD Monoclonal Antibody
| 规格： | / 20μL / 60μL / 120μL |
| 价格： | / ￥580 / ￥1420 / ￥2310 |
货号：E-AB-22126
宿主: Mouse
反应性: H,M,R
应用: IHC-p,IF
Overview
| Synonyms | FAAR,MGC3931,NR1C2,NUC1,NUCI,NUCII,Nuclear hormone receptor 1,Nuclear receptor subfamily 1 group C member 2,Peroxisome proliferative activated receptor delta,Peroxisome proliferator-activated receptor beta (PPAR-beta),Peroxisome proliferator-activated receptor beta,Peroxisome proliferator-activated receptor delta,PPAR beta,PPAR-beta,PPAR-delta,PPAR-ß,PPARB,ppard,PPARD,PPAR Delta Mouse (2F9)抗体 |
| Swissprot | Q03181 |
| Source | Mouse |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant Protein of PPAR Delta of PPAR Delta |
| Application | IHC-p(Detection kit: E-IR-R213),IF |
| Recommended dilution | IHC,,1:100-200;IF,,1:100-200; |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Cellular localization | Nucleus. |
| Tissue specificity | Ubiquitous with maximal levels in placenta and skeletal muscle. |
| Clone No | Clone:5F4 |
|---|---|
| Isotype | IgG |
| Purification | Protein A purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Background | This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway. |
