PPBP Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19288
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
Synonyms | B TG1,Beta TG,Beta thromboglobulin,Beta-TG,C-X-C motif chemokine 7,Chemokine (C X C motif) ligand 7,Connective tissue activating peptide III,CTAP 3,CTAP III,CTAP-III,CTAP-III(1-81),CTAP3,CTAPIII,CXC chemokine ligand 7,CXCL 7,CXCL7,CXCL7,LA PF 4,LA-PF4,LDGF,Leukocyte derived growth factor,Leukocyte-derived growth factor,Low-affinity platelet factor IV,Macrophage-derived growth factor,MDGF,NAP 2,NAP-2,NAP-2(1-63),NAP-2(1-66),NAP-2(73),NAP-2(74),Neutrophil activating peptide 2,Neutrophil-activating peptide 2(1-63),PBP,Platelet basic protein,PPBP,Pro platelet basic protein (chemokine (C-X-C motif) ligand 7),Pro platelet basic protein,SCYB7,Small inducible cytokine subfamily B member 7,Small-inducible cytokine B7,TC1,TC2,TGB,TGB1,THBGB,THBGB1,Thrombocidin 1,Thrombocidin 2,Thromboglobulin,beta-1,PPBP抗体 |
Swissprot | P02775 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Synthetic peptide of human PPBP |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:1000-1:5000;IHC,,1:25-1:100 |
Concentration | 0.8mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | PPBP (Pro-Platelet Basic Protein) is a Protein Coding gene. Diseases associated with PPBP include Erythromelalgia and Colloid Adenoma. Among its related pathways are GPCR Pathway and Peptide ligand-binding receptors. GO annotations related to this gene include growth factor activity and glucose transmembrane transporter activity. An important paralog of this gene is CXCL1. The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. |
Images
Western blot analysis of Human plasma solution using PPBP Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using PPBP Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using PPBP Polyclonal Antibody at dilution of 1:35(×200)