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PPM1K Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-53177

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms BDP,mitochondrial,MSUDMV,PP2C domain containing protein phosphatase 1K,PP2C domain-containing protein phosphatase 1K,PP2C kappa,PP2C like mitochondrial protein,PP2C type mitochondrial phosphoprotein phosphatase,PP2C-kappa,PP2C-like mitochondrial protein,PP2C-type mitochondrial phosphoprotein phosphatase,PP2Ckappa,PP2CM,PPM1K,PPM1K,Protein phosphatase 1K,Protein phosphatase 1K,mitochondrial,Protein phosphatase 2C isoform kappa,Protein phosphatase Mg2+/Mn2+ dependent 1K,PTMP,UG0882E07,PPM1K抗体
    Swissprot Q8N3J5
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Fusion protein of human PPM1K
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:50-1:100
    Concentration 0.78mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Mitochondrion matrix.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore.PPM1K (Protein Phosphatase, Mg2+/Mn2+ Dependent 1K) is a Protein Coding gene. Diseases associated with PPM1K include Maple Syrup Urine Disease, Mild Variant and Intermediate Maple Syrup Urine Disease. Among its related pathways are Valine, leucine and isoleucine degradation and Viral mRNA Translation. GO annotations related to this gene include protein serine/threonine phosphatase activity. An important paralog of this gene is PPM1E.
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