PPP1R3C Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52884
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | OTTHUMP00000020089,Phosphatase 1, regulatory inhibitor subunit 5,PP1 subunit R5,ppp1r3c,PPP1R5 ,PPR3C,Protein phosphatase 1 regulatory subunit 3C,Protein phosphatase 1 regulatory subunit 5,protein phosphatase 1, regulatory (inhibitor) subunit 3C,Protein targeting to glycogen,PTG,R5,PPP1R3C抗体 |
| Swissprot | Q9UQK1 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human PPP1R3C |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:300 |
| Concentration | 0.9mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease. |
