PRDX3 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-14313
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | Antioxidant protein 1,AOP 1,AOP-1,AOP1,HBC189,MER5,MGC104387,MGC24293,mitochondrial,peroxiredoxin 3,Peroxiredoxin III,Peroxiredoxin-3,PRDX3,PRDX3,PRO1748,Protein MER5 homolog,PRX III,Prx-III,PRX3,SP 22,SP-22,SP22,Thioredoxin dependent peroxide reductase mitochondrial,Thioredoxin-dependent peroxide reductase,PRDX3抗体 |
Swissprot | P30048 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant protein of human PRDX3 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
Concentration | 0.2 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Mitochondrion. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene. |
Images
Western Blot analysis of Hela, 293T and MCF7 cell, Human fetal brain tissue and Jurkat cell using PRDX3 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human breast cancer using PRDX3 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human thyroid cancer using PRDX3 Polyclonal Antibody at dilution of 1:50