本公司产品仅供体外研究使用,不用于临床诊断

PRPF8 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-17841

宿主: Rabbit

反应性: H,M

应用: WB

  • 详情
  • Overview

    Synonyms 220 kDa U5 snRNP specific protein,220 kDa U5 snRNP-specific protein,Apoptosis regulated protein 1,Apoptosis regulated protein 2,HPRP8,p220,Pre mRNA processing factor 8,Pre mRNA-processing factor 8, S. cerevisiae, homolog of,Pre-mRNA-processing-splicing factor 8,Precursor mRNA processing protein ,PRP8,PRP8 homolog,PRP8 pre mRNA processing factor 8 homolog ,PRP8,PRPC8,Prpf8,Retinitis pigmentosa 13 (autosomal dominant),RP13,SNRNP220,Splicing factor Prp8,U5 snRNP specific protein ,U5 snRNP specific protein (220 kD), ortholog of S. cerevisiae Prp8p,PRPF8抗体
    Swissprot Q6P2Q9
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Synthetic peptide of human PRPF8
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:500-1:2000;
    Concentration 0.5mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus speckle.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
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