PSMC2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11408
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | 26S protease complex,26S protease regulatory subunit 7,26S proteasome AAA-ATPase subunit RPT1,mammalian suppressor of sgv-1 of yeast,MSS1,Nbla10058,protease 26S subunit 7,proteasome 26S ATPase subunit 2,Proteasome 26S subunit ATPase 2,Proteasome 26S subunit ATPase 2,Protein MSS1,PRS7,PSMC2,putative protein product of Nbla10058,S7,PSMC2抗体 |
| Swissprot | P35998 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human PSMC2 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. |
Images
Western Blot analysis of 231 cell using PSMC2 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human thyroid cancer using PSMC2 Polyclonal Antibody at dilution of 1:25
Immunohistochemistry of paraffin-embedded Human breast cancer using PSMC2 Polyclonal Antibody at dilution of 1:25
