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PTGER1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-15621

宿主: Rabbit

反应性: H,M,R

应用: WB

  • 详情
  • Overview

    Synonyms EP1,PGE receptor EP1 subtype,PGE2 receptor EP1 subtype,Prostaglandin E receptor 1 subtype EP1 42kDa,Prostaglandin E receptor 1 subtype EP1,Prostaglandin E2 receptor EP1 subtype,Prostanoid EP1 receptor,PTGER1,PTGER1抗体
    Swissprot P34995
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Synthetic peptide of human PTGER1
    Application WB(Detection kit: E-IR-R304)
    Recommended dilution WB,,1:200-1:1000;
    Concentration 0.3 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cell Membrane; multi-pass membrane protein.
    Tissue specificity Abundant in kidney. Lower level expression in lung, skeletal muscle and spleen, lowest expression in testis and not detected in liver brain and heart.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin.
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