PTGER1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-15621
宿主: Rabbit
反应性: H,M,R
应用: WB
Overview
Synonyms | EP1,PGE receptor EP1 subtype,PGE2 receptor EP1 subtype,Prostaglandin E receptor 1 subtype EP1 42kDa,Prostaglandin E receptor 1 subtype EP1,Prostaglandin E2 receptor EP1 subtype,Prostanoid EP1 receptor,PTGER1,PTGER1抗体 |
Swissprot | P34995 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human PTGER1 |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:200-1:1000; |
Concentration | 0.3 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell Membrane; multi-pass membrane protein. |
Tissue specificity | Abundant in kidney. Lower level expression in lung, skeletal muscle and spleen, lowest expression in testis and not detected in liver brain and heart. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. |