PTGER4 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12392
宿主: Rabbit
反应性: H
应用: WB
Overview
| Synonyms | EP 4,EP4,EP4R,MGC126583,PE2R4,PGE receptor EP4 subtype,PGE2 receptor EP4 subtype,Prostaglandin E receptor 4,Prostaglandin E receptor 4 subtype EP4,Prostaglandin E2 receptor,Prostaglandin E2 receptor EP4 subtype,Prostanoid EP4 receptor,PTGER 2,PTGER 4,PTGER2,PTGER4,PTGER4抗体 |
| Swissprot | P35408 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human PTGER4 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. |
| Tissue specificity | High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. |
