PTK2B Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15011
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | CADTK,CAK-beta,CAKB,CAKbeta,Calcium regulated non receptor proline rich tyrosine kinase,Calcium-dependent tyrosine kinase,Cell adhesion kinase beta,E430023O05Rik,EC 2.7.10.2,FADK 2,FADK2,FAK2,FAK2,Focal adhesion kinase 2,MGC124628,PKB,Proline-rich tyrosine kinase 2,Protein kinase B,Protein Tyrosine Kinase 2 Beta,Protein-tyrosine kinase 2-beta,PTK,PTK2B,PTK2B protein tyrosine kinase 2 beta,PYK2,RAFTK,RAFTK2,Related adhesion focal tyrosine kinase,PTK2B抗体 |
| Swissprot | Q14289 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human PTK2B |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Cell membrane. Interaction with nephrocystin induces the membrane-association of the kinase. |
| Tissue specificity | Most abundant in the brain, with highest levels in amygdala and hippocampus. Low levels in kidney. Also expressed in spleen and lymphocytes. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. |
Images
Western Blot analysis of Raji cell using PTK2B Polyclonal Antibody at dilution of 1:300
Immunohistochemistry of paraffin-embedded Human brain using PTK2B Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human cervical cancer using PTK2B Polyclonal Antibody at dilution of 1:50
