PTPA Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53148
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | subunit B'',KIAA0044 ,MGC2184 ,Phosphotyrosyl phosphatase activator,PP2A,PP2A phosphatase activator ,PP2A subunit B',PP2A subunit B' isoform PR53,PP2A subunit B' PR53 isoform ,PPP2R4,PR53 ,PR53 isoform,Protein phosphatase 2, regulatory subunit B-prime,Protein phosphatase 2A activator regulatory subunit 4,Protein phosphatase 2A regulatory subunit B' (PR 53),PTPA,PTPA,Serine/threonine protein phosphatase 2A regulatory subunit B' ,Serine/threonine-protein phosphatase 2A activator,Serine/threonine-protein phosphatase 2A regulatory subunit 4,Serine/threonine-protein phosphatase 2A regulatory subunit B'',PTPA抗体 |
| Swissprot | Q15257 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human PTPA |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 1.08mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. |
