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PTPRS Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19112

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms Protein tyrosine phosphatase PTPsigma ,Protein tyrosine phosphatase receptor type S,Protein tyrosine phosphatase receptor type sigma,Ptprs,PTPRS,PTPSIGMA ,R PTP sigma,R-PTP-S,R-PTP-sigma,Receptor-type tyrosine-protein phosphatase S,Receptor-type tyrosine-protein phosphatase sigma,PTPRS抗体
    Swissprot Q13332
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Fusion protein of human PTPRS
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:100-1:300
    Concentration 0.96mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family.PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP.The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains.Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis.This PTP has been also implicated in the molecular control of adult nerve repair.Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
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