Purified Anti-Human CD1a Antibody[OKT-6]
规格: | / 25μg / 100μg |
价格: | / ¥344 / ¥640 |
货号:E-AB-F1126A
货期:咨询
宿主: Mouse
反应性: H
应用: FCM
Overview
Synonyms | R4;CD 1a;CD1A ;T-cell surface glycoprotein CD1a;T6 |
Swissprot | P06126 |
Source | Mouse |
Reactivity | Human |
Application | FCM |
Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
Concentration | 0.5mg/mL |
Clonality | Monoclonal |
Properties
Clone No | OKT-6 |
---|---|
Isotype | Mouse IgG1, κ |
Conjugation | Unconjugated |
Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Background | CD1a is a 49 kD member of the immunoglobulin superfamily also known as T6 and R4. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. CD1a plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1a has been implicated in thymic T cell development. |