Purified Anti-Human CD25 Antibody[BC96]
规格: | / 25μg / 100μg |
价格: | / ¥300 / ¥700 |
货号:E-AB-F11940P
货期:7~10 days
宿主: Mouse
反应性: H
应用: FCM
Overview
Synonyms | IMD;IDDM;IL2RA;CD25;IDDM10;IL2R;IMD41;TCGFR;p55;IL-2 receptor subunit alpha;IL-2R subunit alpha;IL2-RA;IL-2-RA;IL-2Rα;Interleukin-2 receptor subunit alpha;TAC antigen;Tac; p55; IL-2Rαalpha chain;CD25 antigen;IL 2 receptor alpha subunit;IL2 RA;Interleukin 2 receptor;Interleukin 2 receptor alpha;Interleukin 2 receptor alpha chain;t-cell growth factor receptor |
Swissprot | P01589 |
Source | Mouse |
Reactivity | Human |
Immunogen | Recombinant Human CD25 protein |
Application | FCM |
Recommended dilution | FCM,,2 μg/ml(1×10^5-5×10^5 cells) |
Concentration | 1mg/mL |
Clonality | Recombinant |
Properties
Clone No | BC96 |
---|---|
Isotype | Mouse IgG1, κ |
Purification | >98%, Protein A/G purified |
Conjugation | Unconjugated |
Storage instructions | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300 |
Background | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. |