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Purified Anti-Human CD7 Antibody[HIT7]

规格: / 25μg / 100μg
价格: / ¥344 / ¥768

货号:E-AB-F1315A

货期:咨询

宿主: Mouse

反应性: H

应用: FCM

  • 详情
  • Overview

    Synonyms CD7;GP40;T-cell antigen CD7;T-cell leukemia antigen;T-cell surface antigen Leu-9;TP41
    Swissprot P09564
    Source Mouse
    Reactivity Human
    Application FCM
    Recommended dilution FCM,,2 μg/mL(1×10^5-5×10^5 cells)
    Concentration 0.5mg/mL
    Clonality Monoclonal

    Properties

    Clone No HIT7
    Isotype Mouse IgG1, κ
    Conjugation Unconjugated
    Storage instructions This product can be stored at 2-8°C for 12 months. Do not freeze.
    Storage buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
    Background CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.
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