Purified Anti-Human CD7 Antibody[HIT7]
规格: | / 25μg / 100μg |
价格: | / ¥344 / ¥768 |
货号:E-AB-F1315A
货期:咨询
宿主: Mouse
反应性: H
应用: FCM
Overview
Synonyms | CD7;GP40;T-cell antigen CD7;T-cell leukemia antigen;T-cell surface antigen Leu-9;TP41 |
Swissprot | P09564 |
Source | Mouse |
Reactivity | Human |
Application | FCM |
Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
Concentration | 0.5mg/mL |
Clonality | Monoclonal |
Properties
Clone No | HIT7 |
---|---|
Isotype | Mouse IgG1, κ |
Conjugation | Unconjugated |
Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Background | CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion. |