Purified Anti-Human/Mouse IL-5 Antibody[TRFK5]
规格: | / 25μg / 100μg |
价格: | / ¥400 / ¥768 |
货号:E-AB-F1205A
货期:咨询
宿主: Rat
反应性: H;M
应用: ICFCM;ELISA
Overview
Synonyms | B-cell differentiation factor I;IL-5;Interleukin-5;T-cell replacing factor;TRF |
Swissprot | P05113,P04401 |
Source | Rat |
Reactivity | Human;Mouse |
Application | ICFCM;ELISA |
Concentration | 0.5mg/mL |
Clonality | Monoclonal |
Properties
Clone No | TRFK5 |
---|---|
Isotype | Rat IgG1, κ |
Conjugation | Unconjugated |
Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Background | IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5. |