Purified Anti-Mouse CD117/c-Kit Antibody[2B8]
| 规格： | / 25μg / 100μg |
| 价格： | / ￥288 / ￥768 |
货号：E-AB-F1092A
货期：咨询
宿主: Rat
反应性: M
应用: FCM
Overview
| Synonyms | CD117;Kit;Mast/stem cell growth factor receptor Kit;Proto-oncogene c-Kit;SCFR;Tyrosine-protein kinase Kit |
| Swissprot | P05532 |
| Source | Rat |
| Reactivity | Mouse |
| Application | FCM |
| Concentration | 0.5mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | 2B8 |
|---|---|
| Isotype | Rat IgG2b, κ |
| Conjugation | Unconjugated |
| Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Background | CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells. |
