Purified Anti-Mouse CD119 Antibody[GR-20]
| 规格： | / 25μg / 100μg |
| 价格： | / ￥336 / ￥640 |
货号：E-AB-F1115A
货期：咨询
宿主: Rat
反应性: M
应用: FCM
Overview
| Synonyms | CD119;IFN-gamma-R-alpha;IFN-gamma-R1;Ifngr1;Interferon gamma receptor 1 |
| Swissprot | P15261 |
| Source | Rat |
| Reactivity | Mouse |
| Application | FCM |
| Concentration | 0.5mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | GR-20 |
|---|---|
| Isotype | Rat IgG2a, κ |
| Conjugation | Unconjugated |
| Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Background | CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses. |
