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Purified Anti-Mouse CD127/IL-7RA Antibody[A7R34]

规格: / 25μg / 100μg
价格: / ¥400 / ¥640

货号:E-AB-F1023A

货期:咨询

宿主: Rat

反应性: M

应用: FCM

  • 详情
  • Overview

    Synonyms CD127;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;Il7r;Interleukin-7 receptor subunit alpha
    Swissprot P16872
    Source Rat
    Reactivity Mouse
    Application FCM
    Concentration 0.5mg/mL
    Clonality Monoclonal

    Properties

    Clone No A7R34
    Isotype Rat IgG2a, κ
    Conjugation Unconjugated
    Storage instructions This product can be stored at 2-8°C for 12 months. Do not freeze.
    Storage buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
    Background CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.
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