Purified Anti-Mouse CD127/IL-7RA Antibody[A7R34]
规格: | / 25μg / 100μg |
价格: | / ¥400 / ¥640 |
货号:E-AB-F1023A
货期:咨询
宿主: Rat
反应性: M
应用: FCM
Overview
Synonyms | CD127;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;Il7r;Interleukin-7 receptor subunit alpha |
Swissprot | P16872 |
Source | Rat |
Reactivity | Mouse |
Application | FCM |
Concentration | 0.5mg/mL |
Clonality | Monoclonal |
Properties
Clone No | A7R34 |
---|---|
Isotype | Rat IgG2a, κ |
Conjugation | Unconjugated |
Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Background | CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development. |