Purified Anti-Mouse CD161/NK1.1 Antibody[PK136]
| 规格： | / 25μg / 100μg |
| 价格： | / ￥120 / ￥416 |
货号：E-AB-F0987A
货期：咨询
宿主: Mouse
反应性: M
应用: FCM
Overview
| Synonyms | CD161 antigen-like family member C;CD161/NK1.1;CD161c;Killer cell lectin-like receptor subfamily B member 1C;Klrb1c;Ly-55c;NKR-P1 40;NKR-P1.9;NKR-P1C |
| Swissprot | P27814,P27812,Q99JB4 |
| Source | Mouse |
| Reactivity | Mouse |
| Application | FCM |
| Concentration | 0.5mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | PK136 |
|---|---|
| Isotype | Mouse IgG2a, κ |
| Conjugation | Unconjugated |
| Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Background | NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers. |
