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Purified Anti-Mouse CD3ε Antibody[145-2C11]

规格: / 25μg / 100μg
价格: / ¥128 / ¥392

货号:E-AB-F1103A

货期:咨询

宿主: Armenian Hamster

反应性: M

应用: FCM

  • 详情
  • Overview

    Synonyms CD3E;CD3e;T-cell surface antigen T3/Leu-4 epsilon chain;T-cell surface glycoprotein CD3 epsilon chain;T3E
    Swissprot P22646
    Source Armenian Hamster
    Reactivity Mouse
    Immunogen Recombinant Mouse CD3ε protein
    Application FCM
    Recommended dilution FCM,,2 μg/mL(1×10^5-5×10^5 cells)
    Concentration 1mg/mL
    Clonality Monoclonal

    Properties

    Clone No 145-2C11
    Isotype Armenian Hamster IgG
    Purification >98%, Protein A/G purified
    Conjugation Unconjugated
    Storage instructions Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
    Storage buffer Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
    Background CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
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