Purified Anti-Mouse CD3ε Antibody[145-2C11]
规格: | / 25μg / 100μg |
价格: | / ¥128 / ¥392 |
货号:E-AB-F1103A
货期:咨询
宿主: Armenian Hamster
反应性: M
应用: FCM
Overview
Synonyms | CD3E;CD3e;T-cell surface antigen T3/Leu-4 epsilon chain;T-cell surface glycoprotein CD3 epsilon chain;T3E |
Swissprot | P22646 |
Source | Armenian Hamster |
Reactivity | Mouse |
Immunogen | Recombinant Mouse CD3ε protein |
Application | FCM |
Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
Concentration | 1mg/mL |
Clonality | Monoclonal |
Properties
Clone No | 145-2C11 |
---|---|
Isotype | Armenian Hamster IgG |
Purification | >98%, Protein A/G purified |
Conjugation | Unconjugated |
Storage instructions | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
Background | CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. |