Purified Anti-Mouse IL-17A Antibody[17F3]
| 规格： | / 25μg / 100μg |
| 价格： | / ￥480 / ￥768 |
货号：E-AB-F1272A
货期：咨询
宿主: Mouse
反应性: M
应用: ICFCM
Overview
| Synonyms | Ctla9;Il17a;Interleukin-17A |
| Swissprot | Q62386 |
| Source | Mouse |
| Reactivity | Mouse |
| Application | ICFCM |
| Concentration | 0.5mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | 17F3 |
|---|---|
| Isotype | Mouse IgG1, κ |
| Conjugation | Unconjugated |
| Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Storage buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Background | The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-18A in vivo. |
