RAC2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53322
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | EN 7,EN-7,EN7,GX,HSPC 022,HSPC022,p21 Rac 2,p21 Rac2,p21-Rac2,p21Rac2,RAC 2,Rac2,RAC2,Ras related C3 botulinum toxin substrate 2 (rho family,small GTP binding protein Rac2,Ras related C3 botulinum toxin substrate 2,Ras related C3 botulinum toxin substrate 3 (rho family,small GTP binding protein Rac2),Ras related C3 botulinum toxin substrate 3,Ras-related C3 botulinum toxin substrate 2,Rho family small GTP binding protein Rac 2,Rho family small GTP binding protein Rac2,Small G protein,RAC2抗体 |
| Swissprot | P15153 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human RAC2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 1.02mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Membrane-associated when activated. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | RAC2,also named as GX,belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses,such as secretory processes,phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome. |
