RAP1B Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-13928
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | GTP-binding protein smg p21B,K-REV,OK/SW-cl.11,RAL1B,rap1b,RAP1B member of RAS oncogene family,RAP1B,Ras family small GTP binding protein RAP1B,RAS related protein RAP1B,Ras-related protein Rap-1b,Small GTP binding protein,RAP1B抗体 |
Swissprot | P61224 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant protein of human RAP1B |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
Concentration | 0.5 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cell membrane. Cytoplasm>cytosol. Cell junction. May shuttle between plasma membrane and cytosol. Presence of KRIT1 and CDH5 is required for its localization to the cell junction. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. |
Images
Western Blot analysis of 293T, Jurkat and NIH/3T3 cell using RAP1B Polyclonal Antibody at dilution of 1:550
Immunohistochemistry of paraffin-embedded Human thyroid cancer using RAP1B Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human gastric cancer using RAP1B Polyclonal Antibody at dilution of 1:50