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RHOH Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-18792

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms ARHH,GTP binding protein TTF,GTP-binding protein TTF,OTTHUMP00000125213,Ras homolog gene family member H,Rho related GTP binding protein,Rho related GTP binding protein RhoH,Rho-related GTP-binding protein RhoH,RHOH,RHOH,Translocation three four protein,TTF,TTF translocation three four,RHOH抗体
    Swissprot Q15669
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Full length fusion protein
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:40-1:200
    Concentration 1.62mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytoplasm. Cell membrane. Co-localizes together with ZAP70 in the immunological synapse.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes.The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival.This gene may be hypermutated or misexpressed in leukemias and lymphomas.Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts.Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein.
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