RHOH Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18792
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | ARHH,GTP binding protein TTF,GTP-binding protein TTF,OTTHUMP00000125213,Ras homolog gene family member H,Rho related GTP binding protein,Rho related GTP binding protein RhoH,Rho-related GTP-binding protein RhoH,RHOH,RHOH,Translocation three four protein,TTF,TTF translocation three four,RHOH抗体 |
Swissprot | Q15669 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Full length fusion protein |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:40-1:200 |
Concentration | 1.62mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm. Cell membrane. Co-localizes together with ZAP70 in the immunological synapse. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes.The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival.This gene may be hypermutated or misexpressed in leukemias and lymphomas.Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts.Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. |