S100A12 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-11562
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | CAAF1,CAGC,Calcitermin,Calcium-binding protein in amniotic fluid 1,Calgranulin C,Calgranulin-C,Calgranulin-related protein,CGRP,EN RAGE,EN-RAGE,ENRAGE,Extracellular newly identified RAGE-binding protein,migration inhibitory factor-related protein 6,MRP6,Neutrophil S100 protein,p6,Protein S100 A12,S100 calcium binding protein A12,S100 calcium-binding protein A12 (calgranulin C),S100 calcium-binding protein A12,S100A12,S10AC,S100A12抗体 |
| Swissprot | P80511 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human S100A12 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:25-1:100 |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoskeleton,Cytosol,Extracellular region or secreted,extracellular region,Nucleus,Plasma Membrane,Other locations:cytoplasm,secretory granule lumen |
| Tissue specificity | Monocytes and lymphocytes. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. |
