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Serpin E1/PAI-1 Polyclonal Antibody(Capture/Detector)

规格: / 25μg / 100μg
价格: / ¥800 / ¥2100

货号:AN000040P

货期:咨询

宿主: Rabbit

反应性: R

应用: WB;ELISA Capture/Detector

  • 详情
  • Overview

    Synonyms PLasminogen activator inhibitor 1;PAI-1;EndotheLiaL pLasminogen activator inhibitor;Serpin E1;SERPINE1;PLANH1
    Swissprot P20961
    Source Rabbit
    Reactivity Rat
    Immunogen Recombinant Rat Serpin E1/PAI-1 protein expressed by Mammalian
    Application WB(Detection kit: E-IR-R304);ELISA Capture/Detector
    Recommended dilution WB,,1:500-1:1000;ELISA Capture,,2-8 μg/mL;ELISA Detector,,0.1-0.4 μg/mL
    Concentration 1mg/mL
    Clonality Polyclonal

    Properties

    Isotype IgG
    Purification Antigen Affinity Purification
    Conjugation Unconjugated
    Storage instructions Store at 4°C Valid for 1 month or -20°C Valid for 12 months,Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
    Storage buffer Sterile PBS,pH 7.4
    Background Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PlAT) and urokinase-type plasminogen activator (PlAU). As PlAT inhibitor,it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PlAU inhibitor,it is involved in the regulation of cell adhesion and spreading.Acts as a regulator of cell migration,independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells,and regulates odontoblast differentiation and dentin formation during odontogenesis.
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