SERPINA1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14545
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | A1A,A1AT,A1AT,AAT,Alpha 1 antiproteinase,Alpha 1 antitrypsin,Alpha 1 antitrypsin null,Alpha 1 protease inhibitor,Alpha-1 protease inhibitor,Alpha-1-antiproteinase,alpha1 proteinase inhibitor,Alpha1AT,Dom1,PI,PI1,PRO2275,Serine (or cysteine) proteinase inhibitor clade A member 1,Serine protease inhibitor 1-1,Serine protease inhibitor A1a,Serpin A1,Serpin A1a,Serpin peptidase inhibitor clade A member 1,Serpina1,Short peptide from AAT,SPAAT,Spi1-1,SERPINA1抗体 |
| Swissprot | P01009 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human SERPINA1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.3 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted. Endoplasmic reticulum. The S and Z allele are not secreted effectively and accumulate intracellularly in the endoplasmic reticulum and Secreted, extracellular space, extracellular matrix. |
| Tissue specificity | Ubiquitous. Expressed in leukocytes and plasma. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. |
