SLC8A3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12798
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | AW742262,MGC90626,Na+/Ca2+ exchange protein 3,Na+/Ca2+ exchanger 3,NAC3,NCX3,SCL8A3,Sodium calcium exchanger form 3,Sodium/calcium exchanger 3,Sodium/calcium exchanger SLC8A3,Solute carrier family 8 sodium calcium exchanger member 3,SLC8A3抗体 |
| Swissprot | P57103 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human SLC8A3 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane; Multi-pass membrane protein. |
| Tissue specificity | Isoform 2 is expressed in brain and skeletal muscle. Isoform 3 is expressed in excitable cells of brain, retina and skeletal muscle. Isoform 4 is expressed in skeletal muscle.1 Publication |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. |
