SNAI1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-32931
宿主: Rabbit
反应性: H,M,Mk
应用: WB,IHC-p,IF
Overview
| Synonyms | dJ710H13.1,Protein sna,Protein snail homolog 1,Protein snail homolog,SLUGH2,SNA,Sna protein,SNAH,SNAI,snai1,SNAI1,Snail 1 homolog,Snail 1 zinc finger protein,SNAIL,Snail family transcriptional repressor 1,Snail homolog 1 (Drosophila),SNAIL,Drosophila,homolog of,1,SNAIL1,Zinc finger protein SNAI1,SNAI 1抗体 |
| Swissprot | O95863 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Monkey |
| Immunogen | Synthesized peptide derived from human SNAI 1 around the non-phosphorylation site of Ser246. |
| Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),IF |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300;IF,,1:200-1:1000; |
| Concentration | 1mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cytoplasm. Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. |
| Tissue specificity | Expressed in a variety of tissues with the highest expression in kidney. Expressed in mesenchymal and epithelial cell lines. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Background | The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. |
