Snail Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3580 |
货号：E-AB-63597
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | SNAI1,SLUGH2,SNA,SNAH,SNAIL,SNAIL1,dJ710H13.1,SNAI1抗体 |
| Swissprot | O95863 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant fusion protein of human Snail (NP_005976.2). |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,, 1:500-1:2000;IHC,, 1:50-1:200; |
| Concentration | 1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. Cytoplasm. Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20°C. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Background | The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. |
Images
Western blot analysis of extracts of various cell lines using Snail Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Rat kidney using Snail Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human liver using Snail Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse brain using Snail Polyclonal Antibody at dilution of 1:100 (40x lens).
客户发表文献
- 文献: Hyperglycemia promotes Snail-induced epithelial–mesenchymal transition of gastric cancer via activating ENO1 expression
样品类型: Cell lysate - 文献: Proteomic analysis of radio‐resistant breast cancer xenografts: Increased TGF‐β signaling and metabolism
样品类型: MCF-7 cell-xenograft,MCF-D7-6G cell-xenograft
