SNAP25 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14354
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | bA416N4.2,Bdr,CMS18,dJ1068F16.2,FLJ23079,HGNC:11132,MGC105414,MGC139754,Resistance to inhibitors of cholinesterase 4 homolog,RIC 4,RIC4,SEC 9,SEC9,SNAP 25,SNAP,SNAP-25,SNAP-25B,SNAP25,SNP 25,SNP25,SNP25,sp,SUP,Super protein,Synaptosomal associated 25 kDa protein,Synaptosomal associated protein,Synaptosomal associated protein 25,Synaptosomal associated protein 25kDa,Synaptosomal-associated 25 kDa protein,Synaptosomal-associated protein 25,Synaptosomal-associated protein,25-KD,SNAP25抗体 |
| Swissprot | P60880 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human SNAP25 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-200; |
| Concentration | 0.2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm>perinuclear region. Cell membrane. Cell junction>synapse>synaptosome. Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region. |
| Tissue specificity | Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs).The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE.For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two.Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release.Two alternative transcript variants encoding different protein isoforms have been described for this gene. |
