SOCS6 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14359
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
| Synonyms | CIS-4,CIS4,Cish4,Cytokine inducible SH2 protein 4,Cytokine-inducible SH2 protein 4,HSPC060,SOCS-4,SOCS-6,SOCS4,Socs6,SOCS6,SSI4,STAI4,STAT induced STAT inhibitor 4,STAT4,STATI4,Suppressor of cytokine signaling 4,Suppressor of cytokine signaling 6,SOCS6抗体 |
| Swissprot | O14544 |
| Source | Rabbit |
| Reactivity | Human,Mouse |
| Immunogen | Recombinant protein of human SOCS6 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol,Plasma Membrane,immunological synapse,Other locations:cytoplasm |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene contains a SH2 domain and a CIS homolog domain.The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family.CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling.The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells.A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. |
