SPRTN Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-52495
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | C1orf124,CA124,Chromosome 1 open reading frame 124 ,DDDL1880,dJ876B10.3,PRO4323,RP5-876B10.3,Spartan,SprT-like domain at the N terminus,SprT-like N-terminal domain,Zinc finger RAD18 domain-containing protein C1orf124,SPRTN抗体 |
Swissprot | Q9H040 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Fusion protein of human SPRTN |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:300 |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified. |