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TAX1BP1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-10657

宿主: Rabbit

反应性: H,M,R

应用: IHC

  • 详情
  • Overview

    Synonyms 1200003J11Rik,1700069J21Rik,Aa1076,AA930106,CALCOCO 3,CALCOCO3,D6Ertd404e,D6Ertd772e,Human T cell leukemia virus type 1-binding protein,Liver regeneration-related protein LRRG004,MGC94031,PRO0105,T6BP,Tax1 (human T cell leukemia virus type I) binding protein,Tax1 (human T cell leukemia virus type I) binding protein 1,Tax1 binding protein 1,Tax1 binding protein,Tax1-binding protein 1,Tax1-binding protein 1 homolog,TAX1BP1,TAX1BP1 protein,tax1bp1b,TAXB1,TRAF 6 binding protein,TRAF6 binding protein,TRAF6 binding protein T6BP,TRAF6-binding protein,TRAF6-interacting protein,TXBP 151,TXBP151,wu:fc20c12,wu:fc56e11,zgc:73219,zgc:77129,TAX1BP1抗体
    Swissprot Q86VP1
    Source Rabbit
    Reactivity Human,Mouse,Rat
    Immunogen Recombinant protein of human TAX1BP1
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:100-1:300
    Concentration 0.4 mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Cytosol,Extracellular region or secreted,extracellular exosome
    Tissue specificity Expressed in all tissues tested.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
    Background This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[
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