TBX1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53339
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | Brachyury,CAFS,CTHM,DGCR,DGS,DORV,T box,T box 1,T box 1 transcription factor,T box 1 transcription factor C,T box protein 1,T box transcription factor TBX 1,T box transcription factor TBX1,T-box protein 1,T-box transcription factor TBX1,TBX 1,TBX 1C,tbx1,TBX1,TBX1C,Testis specific T box protein,Testis-specific T-box protein,TGA,VCFS,TBX1抗体 |
| Swissprot | O43435 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human TBX1 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:25-1:100; |
| Concentration | 0.7mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
