TCP1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-40159
宿主: Rabbit
反应性: H
应用: WB
Overview
Synonyms | AI528772,c-cpn,CCT alpha,CCT,CCT-alpha,CCT1,Ccta,CCTalpha,D6S230E,MGC133746,p63,T complex 1,T complex protein 1 alpha subunit,T complex protein 1,T-complex homolog TCP1,T-complex protein 1 subunit alpha,T-complex protein 1 subunit alpha B,Tailless complex polypeptide 1,Tailless complex polypeptide 1A,Tailless complex polypeptide 1B,TCP 1 alpha,Tcp-1,TCP-1-alpha,TCP1,TCPA,Tp63,TRic,TCP1抗体 |
Swissprot | P17987 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Recombinant human T-complex protein 1 subunit alpha protein |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:500-1:1000;IHC,,1:50-1:100; |
Concentration | 2mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytoplasm. Cytoplasm>cytoskeleton>centrosome. |
Tissue specificity | Highest expression level in testis |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
Background | The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found. |